ALK-1 (D5F3) FOR NSCLC
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What is this Test About?
A subset of Anaplastic large cell lymphomas show overexpression of Anaplastic lymphoma kinase (ALK-1) protein, resulting from a translocation involving the ALK1 gene. The abnormal ALK-1 expression can be in a nuclear and cytoplasmic distribution. Overexpression of ALK-1 protein is also useful in the diagnosis of Lung adenocarcinoma and Inflammatory myofibroblastic tumor. In normal tissue ALK-1 is negative.
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