CD30 (KI-1 ANTIGEN)
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What is this Test About?
CD30 is used to diagnose Hodgkin lymphoma and also some Non Hodgkin Lymphomas like Anaplastic Large cell Lymphoma. CD30 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. Expression of CD30 can also be seen in Embryonal carcinomas, Malignant melanomas, Mesenchymal tumors and activated T & B lymphocytes and plasma cells. Reed-Sternberg cells of classical Hodgkin lymphoma as well as the neoplastic cells of Anaplastic large cell lymphoma express CD30.
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