PLACENTAL ALKALINE PHOSPHATASE
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What is this Test About?
PLAP (Placental Alkaline Phosphatase) is a marker of Germ cell tumors & is expressed by a variety of tumors like Classic seminoma, Embryonal carcinoma, Yolk sac tumor, Choriocarcinoma & Intratubular germ cell neoplasia. It is sometimes positive in cases of Spermatocytic seminoma. Positive staining is also seen in Dysgerminoma & Gonadoblastoma. Few epithelial tumors like Serous carcinoma also express PLAP.
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