(WT1) WILM'S TUMOR PROTEIN 1
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What is this Test About?
WT1 is a tumor suppressor gene involved in the development of Wilms' tumor. Wild type of WT1 gene performs an oncogenic function. It has been identified as a molecular target for cancer immunotherapy, hence it is a must to test all Wilm' tumors for expression of WT1. Recent studies have shown that WT1 plays an important role in disease progression & prognosis of malignancies such as Acute Myeloid Leukemia & Serous ovarian carcinoma.
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